Annual Meeting at EB 2003
  
at Experimental Biology 2003
Official Guest Society of the American Association of Anatomists
April 11-15
San Diego, California
AAA/CAJAL CLUB SOCIALIZER
Saturday, April 12, 2003
San Diego Marriott Hotel & Marina
PRESENTATION OF KRIEG CORTICAL KUDOS 2003 AWARDS
Sunday, April 13, 2003
San Diego Convention Center
Krieg Cortical Discover Award
Wolf Singer, Ph.D. (Max Planck Institute for Brain Research)
'The putative role of oscillations and synchrony in cortical processing'
Krieg Cortical Explorer Award
Guy N. Elston, Ph.D. (University of Queensland)
'Cortex, cognition and the cell: new insights into the pyramidal cell and prefrontal function'
Krieg Cortical Scholar Award:
David C. Lyon, Ph.D. (Massachusetts Institute of Technology)
'New anatomical evidence for the third visual area: Addressing a 30 year old controversy over primate cortical organization'
CAJAL CLUB BUSINESS MEETING
Sunday, April 13, 2002
San Diego Convention Center
THE NISSL BODY'S POSTER SESSION
Sunday, April 13, 2002
San Diego Convention Center
Chair: Larry Swanson, Ph.D. (University of Southern California)
The Nissl Body's Poster Session will present students displaying posters on their research.
PRESIDENTIAL SYMPOSIUM
Sunday, April 13, 2002
San Diego Convention Center
NEUROBIOLOGY OF REHABILITATION
2:30 pm - 5:30 pm, Room 25BC
Chair: John H. Morrison, Ph.D. (Mt. Sinai School of Medicine)
SPEAKERS:
George W. Huntley, Ph.D. (Mt. Sinai School of Medicine)
'From Maps to Molecules: Plasticity Mechanisms and Their Implications for Neural Repair'
Jeffrey D. Macklis, M.D., Ph.D. (Harvard Medical School/Children's Hospital)
'Cellular Repair of Complex Cortical Circuitry by Neural Precursors'
Mark Tuszynski, M.D., Ph.D. (University of California, San Diego)
'Neurotrophic Factors, Cellular Bridges, and Gene Therapy for Repair of Spinal Cord Injury'
Phyllis M. Wise, Ph.D. (University of California, Davis)
'Neuroprotective Actions of Estrogen in the Adult and During Aging: Insights into Mechanisms of Action'
THIRTY-FIFTH ANNUAL PINCKNEY J. HARMAN MEMORIAL LECTURE
Protein Synthesis at the Synapse: Mechanisms and Role in Synapse Function
Sunday, April 13, 2003
5:30 pm - 6:30 pm, Room 25BC
San Diego Convention Center
Oswald Steward, Ph.D.
University of California, Irvine
Abstract: It has been 20 years since our report describing the selective localization of polyribosomes beneath postsynaptic sites on dendrites (synapse-associated polyribosome complexes or SPRCs). This was a situation where structure strongly implied function, specifically, that SPRCs were the site of synthesis of proteins that were critical for synapse function, and would be ideally situated to provide proteins necessary for synapse growth and plasticity. Subsequent studies revealed that SPRCs were especially prominent at developing synapses, suggesting that local protein synthesis played a key role during periods of synapse growth and plasticity. This idea has subsequently been confirmed and extended by work from a number of labs. I will review what has been learned about the machinery for protein synthesis present at synapses, the mechanisms underlying the selective transport of particular mRNAs into dendrites, the mechanisms underlying the docking of mRNAs at synapses, and the mechanisms regulating the local translation of mRNAs at synapses. I will review our studies documenting the signal transduction pathways through which newly-synthesized mRNAs are transported into dendrites and targeted selectively to synaptic sites that have experienced particular patterns of activity. Finally, I will summarize evidence documenting that protein synthesis at the synapse plays a key role in activity-dependent synaptic modifications (LTP and LTD), and perhaps also in memory storage mechanisms.
NOTE: Other neuroscience sessions can be found among AAA's symposia and platform sessions.
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