Funding Opportunities

Recently announced Requests for Proposals (RFPs), Requests for Applications (RFAs), and other funding opportunities of possible interest to AAA members are listed below by date of posting and remain on the list through the closing date. To search this page for a particular topic, press Ctrl-F, then enter the keyword for which you are searching.

Posted April 19, 2011

Posted March 29, 2011

Posted February 22, 2011

Blueprint for Neuroscience Research Science Education Award (R25)
To fund the development and evaluation of innovative model programs and materials for enhancing knowledge and understanding of neuroscience among K-12 students and their teachers. This program seeks to 1) provide education to youth on neuroscience, and 2) ensure that highly trained scientists will be available in adequate numbers to address the Nation's research needs in neuroscience. The award provides support for the formation of partnerships between scientists and educators for the development and evaluation of programs and materials that will enhance knowledge and understanding of neuroscience. The intended focus is on topics not well addressed in existing efforts by educational, community, or media activities. Letter of intent due March 11; application due April 11.

Notice of Intent to Publish a Funding Opportunity Announcement for Induced Pluripotent Stem Cell (iPSC) Resources promoting Translational Research Advancements in Neurodegenerative Diseases (U24)
NINDS FOA anticipated spring 2011 to promote the continued development of publically available, well characterized induced pluripotent stem cell (iPSC) research resources that will enable and encourage collaborative research among academic and industry investigators and ultimately accelerate basic science discoveries and therapeutic development for late-onset neurodegenerative diseases. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

Ribosomal Disorders and Their Role in Inherited Bone Marrow Failure Syndromes (R01)
To extend our understanding of the molecular and cellular mechanisms underlying ribosomal disorders, their preferential effects on hematopoiesis and their role in bone marrow failure syndromes. Standard application dates.

Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (Parent F32) (PA-11-113)
Standard application dates.

NHLBI Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral MD/PhD Fellows (F30)
Standard application dates.

Posted February 8, 2011

Lasker Clinical Research Scholars Program (SI2)

This program offers a unique bridge between the NIH intramural and extramural research communities, and contains two phases.  In the first phase, Lasker scholars receive appointments for up to 5-7 years as tenure-track investigators within the NIH Intramural Research Program with independent research budgets.  In the second phase, successful scholars are eligible to apply for up to 5 years of NIH support for their research at an extramural research facility; or, the scholar can be considered to remain as an investigator within the intramural program. Applications due April 4.

International Neuroscience Fellowship (F05)

To advance the training of qualified foreign neuroscientists and clinicians at the early or mid-career level, by enhancing their basic, translational or clinical research skills in a research setting in the United States.  All applicants must be from a low- to middle-income country based on Gross National Income per capita classified by the World Bank ( http://go.worldbank.org/K2CKM78CC0 ). Applications due August 16.

Posted January 31, 2011

A GenitoUrinary Development Molecular Anatomy Project (GUDMAP) (U01)
Through the efforts of the GenitoUrinary Development Molecular Anatomy Project (GUDMAP) consortium, substantial progress has been made in establishing a molecular anatomy atlas of the developing murine kidney. This has provided a significant resource in support of research in kidney development, repair, and regeneration. However, there remain significant gaps within the atlas in the areas of the developing lower urinary tract (ureter, bladder, urethra, sphincter, and prostate) and the developing vascular and nervous system associated with the organs of the urinary tract. NIDDK invites applications for Cooperative Agreement Research Projects (U01) that focus on defining the molecular anatomy of the developing murine lower urinary tract, or the innervation and vasculature of the lower urinary tract organs. Applications are due April 7.

Posted December 20, 2010

NIH Summer Research Experience Programs (R25)

To provide a high quality research experience for high school and college students and for science teachers during the summer academic break, thereby attracting young students to careers in science; providing opportunities for college students to gain valuable research experience to help prepare them for graduate school; and enhancing the skills of science teachers. Prospective applicants should contact staff at the relevant IC (see Section VII ) to discuss their proposed program.  Applications due Feb. 1 and Aug. 1, 2011.

Advanced In Vivo Imaging to Understand Cancer Systems (R01) 

To promote and support new collaborative projects that focus on the integration of advanced in vivo imaging technologies with systems biology approaches to understand complex cancer phenomena at highest resolution. Letters of intent du Jan. 23; applications due Feb. 23, 2011.

Request for Information: Input to the National Eye Institute Plan, Vision Research in 2011: Needs, Gaps, and Opportunities

NEI invites the scientific vision community, health professionals, patient advocates, professional societies, and the general public to provide suggestions on the following topics:  What are the most significant scientific discoveries in vision research that have occurred since 2004?  What are the most significant scientific research needs, gaps, and opportunities that should be addressed by the NEI?
Responses due Feb. 1, 2011.

Shared Instrumentation Grant Program (S10)

NCRR encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instrumentation or an integrated system that costs at least $100,000. The maximum award is $600,000. Types of instruments supported include confocal and electron microscopes, biomedical imagers, mass spectrometers, DNA sequencers, biosensors, cell-sorters, X-ray diffraction systems, and NMR spectrometers among others.  Applications due Mar. 23, 2011

Posted November 16, 2010

Methods and Approaches for Detection of Gene-Environment Interactions in Human Disease (R21)
To develop and test innovative statistical and bioinformatics methods and analytical strategies and study designs for identifying gene-environment interactions for complex human diseases.  Letter of intent due January 4; application due February 3.

Posted November 1, 2010

Getting from Genes to Function in Lung Disease (R01)
NHLBI seeks applications from institutions/organizations that propose to characterize the function of gene(s) and their associated variants identified by genome-wide association studies (GWAS) or other genetic approaches to be involved in lung diseases. Studies should use integrated approaches across scientific disciplines to determine the pathobiological function of these genes. Application due Feb. 5, 2011, by 5:00 PM local time of applicant organization.

Posted October 26, 2010

New Time Limit for NIH Resubmission Applications

Training in Computational Neuroscience: From Biology to Model and Back Again (T90/R90)
To support integrated research education and research training programs that provide interdisciplinary training in basic neuroscience and the theoretical and technological approaches of computational neuroscience. Application due Jan. 13, 2011.

Training in Neuroimaging: Integrating First Principles and Applications (T90/R90)
To enable the development of novel, interdisciplinary training programs that integrate comprehensive training in basic neuroscience, the physical and biological bases of neuroimaging, the technologies of in vivo neuroimaging, and the application of these technologies to understanding questions in neuroscience across the life span. Letter of intent due Dec. 13; application due Jan. 13, 2011.

Animal and Biological Material Resource Centers (P40)
To provide support for special colonies of laboratory animals, as well as other resources such as reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community at large.

Posted September 7, 2010

A GenitoUrinary Development Molecular Anatomy Project (GUDMAP) Database and Website (U01)
Development NIDDK and the NICHD request applications for maintenance and upgrading of the NIH-sponsored GenitoUrinary Development Molecular Anatomy Project (GUDMAP) database and website, an on-line resource which houses the anatomical and gene expression data generated from GUDMAP molecular atlas research projects. Letter of intent due Oct. 20; application due Nov. 17.

NIDCR Small Grant Program for New Investigators (R03)
Supports basic and clinical research of scientists who are in the early stages of establishing an independent research career in oral, dental, and craniofacial research. This R03 grant mechanism supports pilot or feasibility studies and developmental research projects with the intention of obtaining sufficient preliminary data for a subsequent Investigator-initiated Research Project Grant (R01) application.

Status of Applications and Awards Involving Human Embryonic Stem Cells, and Submissions of Stem Cell Lines for Eligibility Consideration

Clarification on the Roles of NIH Scientific Review Groups (SRG) and Institutional Animal Care and Use Committees (IACUC) in Review of Vertebrate Animal Research

Developing and Improving Institutional Animal Resources (G20)
NCRR solicits applications to renovate, repair, or improve individual animal resources. It is expected that all award funds will be expended expeditiously and that applicants will consider the use of “green” technologies and design approaches. Application due Nov. 4.

Posted August 23, 2010

Mechanisms Mediating Changes in Central Regulation of Bone Mass (R01)
NIA seeks proposals to investigate neural, neuroendocrine, and/or related integrative physiological mechanisms that mediate age dependent changes in bone metabolism and health. The discovery that leptin, secreted by adipocytes, regulates bone mass through a central relay involving serotonergic neurons has generated considerable interest and raised many additional questions about the identity of neural mediator(s) linking the brain to skeletal physiology as well as the potential involvement of other factors whether they be neural/hypothalamic factors (Serotonin, TSH and FSH, ephrins, dynorphins, endocannabiniods/receptors) or other factors such as ACTH, as well as distant tissues/organs such as adipose tissue) in regulating bone mass as well as distant tissues/organs. In addition, recent reports indicate that direct innervations are important in mechanical load sensing and bone remodeling. Letters of intent due Sept. 14; applications due Oct. 14.

Advanced Technologies for Detection of Perturbation-Induced Cellular Signatures (U01)
To develop or substantially adapt technologies and methodologies designed to significantly improve the functionality, quality, scope, and/or throughput of perturbation-induced cellular signature data generation. Letter of intent due Jan. 22; application due Feb. 22.

Support of NIGMS Program Project Grants (P01)
To conduct research which aims to solve a significant biological problem, important for the mission of NIGMS, through a collaborative approach involving outstanding scientists who might not otherwise collaborate.

Mechanisms Mediating Changes in Central Regulation of Bone Mass (R01)
NIA) sees proposals to investigate neural, neuroendocrine and/or related integrative physiological mechanisms that mediate age dependent changes in bone metabolism and health. Letter of intent due Sept. 14; application due Oct. 14.

Advanced Technologies for Detection of Perturbation-Induced Cellular Signatures (U01)
To develop or substantially adapt technologies and methodologies designed to significantly improve the functionality, quality, scope, and/or throughput of perturbation-induced cellular signature data generation. Letter of intent due Jan. 22; application due Feb. 22.

NIH Common Fund Transformative Research Projects Program (R01)
Applications from institutions/organizations proposing groundbreaking, exceptionally innovative, high risk, original and/or unconventional research with the potential to create new scientific paradigms or challenge existing ones. Projects must clearly demonstrate potential to produce a major impact in a broad area of biomedical or behavioral research. Letter of intent due Sept. 27; application due Oct. 27.

Chimpanzee Biomedical Research Program Limited Competition (U42)
NCRR is issuing this limited competition FOA requesting cooperative agreement applications (U42) from the current participating institutions in the NCRR-supported Chimpanzee Biomedical Research Program (CBRP) or institutions currently funded to support NCRR-owned and NCRR-supported/institution-owned chimpanzees. The existing CBRP was established in 1986. The recipient organizations have a responsibility to maintain NCRR colonies of chimpanzees that are, have been, or will be used in NIH-sponsored research. Application due Dec. 06.

NICHD Program Project Grant (P01)
To conduct research on reproductive, developmental, behavioral, social, and rehabilitative processes that determine the health or functioning of newborns, infants, children, adults, families, and populations.

Posted July 30, 2010

Epigenomic Modifications in Neurodevelopment (R01)
NIMH seeks applications that characterize epigenetic events involved in neurodevelopmental processes or propose to identify epigenome-wide marks associated with early environmental influences and vulnerability to mental disorders. Letter of intent due Sept. 20; application due Oct. 20. See also related R21.

2011 NIH Directors New Innovator Award Program (DP2)
Support a small number of early stage investigators of exceptional creativity who propose bold and highly innovative new research approaches that have the potential to produce a major impact on broad, important problems in biomedical and behavioral research. Application due Sept. 20.

Informatics, Coordination and Service Center for the Mutant Mouse Regional Resource Centers (U42)
NCRR seeks applications from institutions/organizations to establish and further develop and implement the ICSC component of the Mutant Mouse Regional Resource Center (MMRRC) program. Application due Oct. 7,

Request for Information (RFI): Tools and Resources for Neuroscience Research
NINDS is soliciting input from the neuroscience and neurological disease research and advocacy communities to identify areas of greatest need and recommend how NINDS might best facilitate the development of these tools/resources.

Instrument Development for Biomedical Applications (R21)
NCRR seeks innovative applications for the development of new or improved instrumentation for biomedical research. Projects should propose tools that can be used by a wide range of biomedical or clinical researchers, and not limited to a specific organ or disease. Application due Oct. 8.

National Institute of Biomedical Imaging and Bioengineering Program Project (P01) Applications
NIBIB seeks applications from institutions/organizations in the broad areas of biomedical imaging and bioengineering enabled by relevant areas of the physical sciences, engineering, computer sciences, information science, and the medical and life sciences. P01 grants are to support broad-based multidisciplinary research programs, which have a well-defined major objective or central theme, but which are addressing a range of imaging or bioengineering questions in contrast to the traditional research project (R01).

Bioengineering Research Partnerships (BRP)[R01]
For basic, applied, and translational multi-disciplinary research that addresses important biological, clinical or biomedical research problems. In the context of this program, a partnership is a multi-disciplinary research team, that applies an integrative, systems approach to develop knowledge and/or methods to prevent, detect, diagnose, or treat disease or to understand health and behavior.

Developmental Mechanisms of Human Structural Birth Defects (P01)
NICHD seeks innovative, multidisciplinary, interactive, and synergistic applications from institutes/organizations that propose to integrate basic, translational, and clinical approaches to understanding the developmental biology and genetic basis of congenital structural human malformations. Letter of intent due Oct. 30; application due Nov. 30.

Posted July 12, 2010

2011 NIH Directors Pioneer Award Program (DP1)
Supports individual scientists of exceptional creativity who propose pioneering and possibly transforming approaches to addressing major biomedical or behavioral challenges. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator’s laboratory or elsewhere. Awardees must commit the major portion (at least 51%) of their research effort to activities supported by the Pioneer Award. Opening date August 13; applications due September 13.

Structural Biology of Membrane Proteins (R01)
Encourages grant applications from institutions/organizations that propose to develop research and methods to enhance the rate of membrane protein structure determination and to determine specific membrane protein structures. Innovative methods for expression, oligomerization, solubilization, stabilization, purification, characterization, crystallization, isotopic labeling, and structure determination of unique and biologically significant membrane proteins by x-ray diffraction, nuclear magnetic resonance (NMR), electron microscopy, mass spectrometry, and other biophysical techniques are encouraged. Opening date September 5; regular application dates.

Clarification of Research Objectives for NIDDK PAR-08-139: Enhancing Zebrafish Research with Research Tools and Techniques (R01)
Applications will be accepted that seek to develop novel tools and methods for high-throughput phenotypic screening to support the characterization of mutants generated by large-scale mutagenesis projects. The focus of the application must be restricted to development of the screening tool and a small pilot or validation screen. Large-scale screening efforts and the establishment of screening centers as community resources remain outside the scope of this FOA.

Modification: PAR-10-153 - NIBIB Biomedical Technology Resource Centers (P41)
FOA PAR-10-153 is changed as follows: There is no budget cap for this FOA. Applicants requesting $500,000 (direct costs) or more in any year must follow the provided instructions.

NEI Center Core Grants for Vision Research (P30)
An NEI P30 Center Core Grant combines one or more research modules for a group of R01 investigators to enhance their research, consolidate resources, avoid duplication of efforts, and/or contribute to cost effectiveness by providing a service with lower cost or higher quality than could be attempted for independent projects by several individual PIs. This program is designed to enhance an institution's environment and capability to conduct vision research and to facilitate collaborative studies of the visual system and its disorders. Applications due September 27, 2010, 2011, 2012.

Pre-application for a Biomedical Technology Research Center (X02)
NCRR encourages pre-applications for centers to conduct research and development on new technology and new/improved instruments driven by the needs of basic, translational, and clinical researchers. Opening datae November 14; applications due December 14; May 11, 2011; December 13, 2011; May 11, 2012; December 13, 2012

Biomedical Technology Research Center (P41)
NCRR encourages grant applications for centers conduct research and development on new technologies and new/improved instruments driven by the needs of basic, translational, and clinical researchers. Standard application dates.

Posted June 29, 2010

Notice of Intent to Publish a Request for Applications for Knockout Mouse Production and Cryopreservation (U54)

Notice of Intent to Publish a Request for Applications for a Knockout Mouse Phenotyping Project Database (U54)

Notice of Intent to Publish a Request for Applications for Knockout Mouse Phenotyping (U54)

Cell Lineage Determination and Tissue Homeostasis in the Aged (R01)
To track cell lineages and to determine cell life spans in normal tissue homeostasis and in response to injury or disease in the elderly. Will support basic and applied research projects for the determination of cell life spans and cell fates in various tissues of aged mammals, specifically in humans or in model organisms (e.g., rodents, dogs or nonhuman primates). Letters of intent due Sept. 7; applications due Oct. 7.

New Strategies for Growing 3D Tissues (R01)
NHLBI and NIBIB National Institutes of Health seek to improve our understanding of how cells respond to their environment and to develop accurate assays and methods to understand how organogenesis may instruct the creation of functional 3D engineered cellular aggregates. Letters of intent due Aug. 2; applications due Sept. 1. Also see related R21.

Posted June 3, 2010

Core Centers for Musculoskeletal Biology and Medicine (P30)
NIAMS invites applications for Research Core Centers to provide shared facilities and services to groups of established, currently funded investigators addressing scientific problems in musculoskeletal biology and medicine, in order to improve efficiency, accelerate the pace of research, and ensure greater productivity. Letters of intent due Sept. 1; applications due Oct. 1.

NCRR Science Education Partnership Award (SEPA) (R25)
NCRR encourages applications for the development and evaluation of innovative research education programs to improve PreK-12 research career opportunities and the community's understanding of the health science advances supported by NIH. Letters of intent due June 28, 2010; May 22, 2011; May 22, 2012/ Applications due July 28, 2010; June 22, 2011; June 22, 2012.

Posted May 24, 2010

Notice of Intent to Publish a Request for Applications for Epigenomic Modifications in Neurodevelopment (R01)

Notice of Intent to Publish a Request for Applications for Epigenomic Modifications in Neurodevelopment (R21)

Notice of Intent to Publish a Request for Applications for Unbiased In Vitro Analysis of Neurobiological Function (R01)

The Central Processing of Taste Information (R01)
NIDCD seeks applications from institutions/organizations studying the role of the central nervous system in the processing of taste information and the perception of taste quality. Opening date: Sept. 5, 2010.

NIGMS National Centers for Systems Biology (P50)
NIGMS seeks grant applications from institutions/ organizations proposing to establish Centers of Excellence in Systems Biology. Letters of intent due Sept.28; applications due Oct. 27, 2010.

NIH Blueprint for Neuroscience Research Competitive Revisions for Studies Focused on Neuropathic Pain or Neural Plasticity to Promote Collaborative Pain Research (R01)
To facilitate the partnering of pain scientists and non-pain neuroscientists from the field of neural plasticity to capture insights and expertise from disciplines where transitions from health to disease have been extensively examined. An expected outcome of this FOA will be the formation of partnerships between pain researchers and non-pain neuroscientists to develop new collaborations focused on understanding the maladaptive neuroplastic changes that occur during the transition from acute to chronic pain. Applications due Sept. 28, 2010, 2011, 2012

Posted May 11, 2010

Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01)

NIH-NSFseek to stimulate quantitative and physical scientists to work with biomedical scientists to transform technological innovation and basic knowledge in the quantitative sciences into new or improved devices or systems for health care. Letters of intent due April 18, 2010, 2011, 2012; applications due May 18, 2010, 2011, 2012.

New Biomedical Frontiers at the Interface of the Life and Physical Sciences (R01)

NIH-NSFseek to encourage grant applications from institutions/organizations that propose discovery research that may create entirely new areas of biomedical investigation through bridging the physical and life/behavioral sciences.   Letters of intent due April 18, 2010, 2011, 2012; applications due May 18, 2010, 2011, 2012.

Instructions for Completion and Peer Review of the Vertebrate Animal Section (VAS) in NIH Grant Applications and Cooperative Agreements

Amended NIH Policy on Submission of Late Grant Application Materials Prior to Initial Peer Review

The Role of Cellular Organelles in Alcohol-Induced Tissue Injury (R01)
T o study biological processes involving the cellular organelles in alcohol-induced tissue injury to: (1) better understand how acute or chronic alcohol consumption affects the structure and function of cellular organelles, and in turn, how these changes contribute to alcohol-induced injury; (2) investigate how variations of proteins in cellular organelles, or their regulation and function, including cellular signaling pathways, contribute to an individual's response to acute or chronic alcohol intake and alcohol-induced tissue injury; (3) develop potential biomarkers for prognosis and diagnosis of tissue injury, or identify new targets for therapeutic interventions.  Opening date: May 5.  See also related R21.

Stress Pathways in Alcohol Induced Organ Injury and Protection (R01)
NIAAA  seek applications that propose studying the role of cellular stress responses, the cytoplasmic classical stress response or heat shock response (HSR) and the endoplasmic reticulum (ER) stress, in alcohol-induced tissue injury and tissue protection.  See also related R21.

Development of Animal Models and Related Biological Materials For Research (R21)
NCRR encourages applications from institutions/ organizations that propose to develop, characterize or improve animal models for human disease or to improve diagnosis and control diseases of laboratory animals that may interfere with research.  Opening date:   May 16.

NIH Expands Provisions of the Streamlined Noncompeting Award Process (eSNAP) and Requires Electronic Submission of SNAPs Beginning August 1, 2010

Program Project on Alcohol-Related Research (P01)
NIAAA Program Project Initiative provides leadership in conducting and fostering interdisciplinary research on a wide variety of topics including, but not limited to: the nature, causes, consequences, diagnosis, treatment, and prevention of alcohol abuse and alcoholism; and in developing new topics, approaches and methodologies to pursue these areas of research.  Letters of intent due Nov. 2; applications due Dec. 2.

Posted April 12, 2010

Posted March 22, 2010

Posted March 19, 2010

Forensic DNA Research and Development Grants
Department of Justice (DOJ) seeks applications R&D that can enhance the forensic uses of DNA technology in criminal justice settings. This solicitation focuses on development of technologies that result in faster, more robust, more informative, less costly, or less labor-intensive identification, collection, preservation, and/or analysis of biological evidence that has the potential for DNA analysis. Applications are due by 11:45 p.m. EDT on April 2.

Common Pathogenetic Mechanisms Of Lung Cancer And COPD (R01)
NHLBI and NCI seek to identify the fundamental etiopathogenetic commonalities between lung cancer and Chronic Obstructive Pulmonary Disease (COPD) to characterize: (a) the genotypic and phenotypic characteristics that determine individual susceptibility; and (b) the shared biochemical, molecular, and immunological pathways involved in the origin and progression of the two diseases. Letters of intent due May 18;
applications due June 18.

Notice of Availability of Administrative Supplements for Roadmap Assay Development for HTS Awards
NINDS will accept requests until the end of August 2010; they will be reviewed on a monthly basis.

NINDS Announces Availability of Funds for Competitive Revision Applications for Grand Challenge on Optimal Cortical Control of DARPA Revolutionizing Upper-Limb Prosthetics (R01 and R37)
Relates to Grand Challenge on achieving optimal electrocorticography (ECoG) based cortical control of the Revolutionizing Upper-limb Prosthetics 2009 developed by the DARPA. Applications due May 12.

Collaborative Research for Molecular and Genomic Studies of Behavior in Animal Models (R01)
NIGMS and NICHD seek to facilitate collaborative research involving behavioral scientists and investigators with expertise in molecular biology and/or genomics addressing questions about the mechanisms of behavior in animal models. Applications from multiple PIs are encouraged.
Opening Date: May 5.

Strategic Partnering to Evaluate Cancer Signatures [SPECS II] (U01)
NCI encourages grant applications for support of the clinical application of multi-analyte molecular signatures derived from comprehensive molecular annotation of tumors. Letters of intent due May 15, 2010; May 15, 2011, May 15, 2012; applications due June 15, 2010, June 15, 2011, June 15, 2012.