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Funding Opportunities
Recently announced Requests for Proposals (RFPs), Requests for Applications (RFAs), and other funding opportunities of possible interest to AAA members are listed below by date of posting and remain on the list through the closing date. To search this page for a particular topic, press Ctrl-F, then enter the keyword for which you are searching.
Posted August 23, 2010
Neurobiology of Migraine (R01)
NINDS NIDCD, NIDCR, and NIEHS seek proposals for innovative research that will expand our current knowledge of neurobiological mechanisms underlying migraine headache, examine the role of neuromodulators, genetic and environmental influences in migraine susceptibility, and explore new targets for therapy development. Also see related R21.
Mechanisms Mediating Changes in Central Regulation of Bone Mass (R01)
NIA seeks proposals to investigate neural, neuroendocrine, and/or related integrative physiological mechanisms that mediate age dependent changes in bone metabolism and health. The discovery that leptin, secreted by adipocytes, regulates bone mass through a central relay involving serotonergic neurons has generated considerable interest and raised many additional questions about the identity of neural mediator(s) linking the brain to skeletal physiology as well as the potential involvement of other factors whether they be neural/hypothalamic factors (Serotonin, TSH and FSH, ephrins, dynorphins, endocannabiniods/receptors) or other factors such as ACTH, as well as distant tissues/organs such as adipose tissue) in regulating bone mass as well as distant tissues/organs. In addition, recent reports indicate that direct innervations are important in mechanical load sensing and bone remodeling. Letters of intent due Sept. 14; applications due Oct. 14.
Advanced Technologies for Detection of Perturbation-Induced Cellular Signatures (U01)
To develop or substantially adapt technologies and methodologies designed to significantly improve the functionality, quality, scope, and/or throughput of perturbation-induced cellular signature data generation. Letter of intent due Jan. 22; application due Feb. 22.
Support of NIGMS Program Project Grants (P01)
To conduct research which aims to solve a significant biological problem, important for the mission of NIGMS, through a collaborative approach involving outstanding scientists who might not otherwise collaborate.
Mechanisms Mediating Changes in Central Regulation of Bone Mass (R01)
NIA) sees proposals to investigate neural, neuroendocrine and/or related integrative physiological mechanisms that mediate age dependent changes in bone metabolism and health. Letter of intent due Sept. 14; application due Oct. 14.
Advanced Technologies for Detection of Perturbation-Induced Cellular Signatures (U01)
To develop or substantially adapt technologies and methodologies designed to significantly improve the functionality, quality, scope, and/or throughput of perturbation-induced cellular signature data generation. Letter of intent due Jan. 22; application due Feb. 22.
NIH Common Fund Transformative Research Projects Program (R01)
Applications from institutions/organizations proposing groundbreaking, exceptionally innovative, high risk, original and/or unconventional research with the potential to create new scientific paradigms or challenge existing ones. Projects must clearly demonstrate potential to produce a major impact in a broad area of biomedical or behavioral research. Letter of intent due Sept. 27; application due Oct. 27.
Chimpanzee Biomedical Research Program Limited Competition (U42)
NCRR is issuing this limited competition FOA requesting cooperative agreement applications (U42) from the current participating institutions in the NCRR-supported Chimpanzee Biomedical Research Program (CBRP) or institutions currently funded to support NCRR-owned and NCRR-supported/institution-owned chimpanzees. The existing CBRP was established in 1986. The recipient organizations have a responsibility to maintain NCRR colonies of chimpanzees that are, have been, or will be used in NIH-sponsored research. Application due Dec. 06.
NICHD Program Project Grant (P01)
To conduct research on reproductive, developmental, behavioral, social, and rehabilitative processes that determine the health or functioning of newborns, infants, children, adults, families, and populations.
Posted July 30, 2010
IACUC 101 and 201 PLUS Workshops: August 18-19, 2010 in San Francisco, CA
Epigenomic Modifications in Neurodevelopment (R01)
NIMH seeks applications that characterize epigenetic events involved in neurodevelopmental processes or propose to identify epigenome-wide marks associated with early environmental influences and vulnerability to mental disorders. Letter of intent due Sept. 20; application due Oct. 20. See also related R21.
2011 NIH Directors New Innovator Award Program (DP2)
Support a small number of early stage investigators of exceptional creativity who propose bold and highly innovative new research approaches that have the potential to produce a major impact on broad, important problems in biomedical and behavioral research. Application due Sept. 20.
Informatics, Coordination and Service Center for the Mutant Mouse Regional Resource Centers (U42)
NCRR seeks applications from institutions/organizations to establish and further develop and implement the ICSC component of the Mutant Mouse Regional Resource Center (MMRRC) program. Application due Oct. 7,
Request for Information (RFI): Tools and Resources for Neuroscience Research
NINDS is soliciting input from the neuroscience and neurological disease research and advocacy communities to identify areas of greatest need and recommend how NINDS might best facilitate the development of these tools/resources.
Instrument Development for Biomedical Applications (R21)
NCRR seeks innovative applications for the development of new or improved instrumentation for biomedical research. Projects should propose tools that can be used by a wide range of biomedical or clinical researchers, and not limited to a specific organ or disease. Application due Oct. 8.
National Institute of Biomedical Imaging and Bioengineering Program Project (P01) Applications
NIBIB seeks applications from institutions/organizations in the broad areas of biomedical imaging and bioengineering enabled by relevant areas of the physical sciences, engineering, computer sciences, information science, and the medical and life sciences. P01 grants are to support broad-based multidisciplinary research programs, which have a well-defined major objective or central theme, but which are addressing a range of imaging or bioengineering questions in contrast to the traditional research project (R01).
Bioengineering Research Partnerships (BRP)[R01]
For basic, applied, and translational multi-disciplinary research that addresses important biological, clinical or biomedical research problems. In the context of this program, a partnership is a multi-disciplinary research team, that applies an integrative, systems approach to develop knowledge and/or methods to prevent, detect, diagnose, or treat disease or to understand health and behavior.
Developmental Mechanisms of Human Structural Birth Defects (P01)
NICHD seeks innovative, multidisciplinary, interactive, and synergistic applications from institutes/organizations that propose to integrate basic, translational, and clinical approaches to understanding the developmental biology and genetic basis of congenital structural human malformations. Letter of intent due Oct. 30; application due Nov. 30.
Posted July 12, 2010
2011 NIH Directors Pioneer Award Program (DP1)
Supports individual scientists of exceptional creativity who propose pioneering and possibly transforming approaches to addressing major biomedical or behavioral challenges. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator’s laboratory or elsewhere. Awardees must commit the major portion (at least 51%) of their research effort to activities supported by the Pioneer Award. Opening date August 13; applications due September 13.
Structural Biology of Membrane Proteins (R01)
Encourages grant applications from institutions/organizations that propose to develop research and methods to enhance the rate of membrane protein structure determination and to determine specific membrane protein structures. Innovative methods for expression, oligomerization, solubilization, stabilization, purification, characterization, crystallization, isotopic labeling, and structure determination of unique and biologically significant membrane proteins by x-ray diffraction, nuclear magnetic resonance (NMR), electron microscopy, mass spectrometry, and other biophysical techniques are encouraged. Opening date September 5; regular application dates.
Clarification of Research Objectives for NIDDK PAR-08-139: Enhancing Zebrafish Research with Research Tools and Techniques (R01)
Applications will be accepted that seek to develop novel tools and methods for high-throughput phenotypic screening to support the characterization of mutants generated by large-scale mutagenesis projects. The focus of the application must be restricted to development of the screening tool and a small pilot or validation screen. Large-scale screening efforts and the establishment of screening centers as community resources remain outside the scope of this FOA.
Modification: PAR-10-153 - NIBIB Biomedical Technology Resource Centers (P41)
FOA PAR-10-153 is changed as follows: There is no budget cap for this FOA. Applicants requesting $500,000 (direct costs) or more in any year must follow the provided instructions.
NEI Center Core Grants for Vision Research (P30)
An NEI P30 Center Core Grant combines one or more research modules for a group of R01 investigators to enhance their research, consolidate resources, avoid duplication of efforts, and/or contribute to cost effectiveness by providing a service with lower cost or higher quality than could be attempted for independent projects by several individual PIs. This program is designed to enhance an institution's environment and capability to conduct vision research and to facilitate collaborative studies of the visual system and its disorders.
Applications due September 27, 2010, 2011, 2012.
Pre-application for a Biomedical Technology Research Center (X02)
NCRR encourages pre-applications for centers to conduct research and development on new technology and new/improved instruments driven by the needs of basic, translational, and clinical researchers. Opening datae November 14; applications due December 14; May 11, 2011; December 13, 2011; May 11, 2012; December 13, 2012
Biomedical Technology Research Center (P41)
NCRR encourages grant applications for centers conduct research and development on new technologies and new/improved instruments driven by the needs of basic, translational, and clinical researchers. Standard application dates.
Posted June 29, 2010
Notice of Intent to Publish a Request for Applications for Knockout Mouse Production and Cryopreservation (U54)
Notice of Intent to Publish a Request for Applications for a Knockout Mouse Phenotyping Project Database (U54)
Notice of Intent to Publish a Request for Applications for Knockout Mouse Phenotyping (U54)
Cell Lineage Determination and Tissue Homeostasis in the Aged (R01)
To track cell lineages and to determine cell life spans in normal tissue homeostasis and in response to injury or disease in the elderly. Will support basic and applied research projects for the determination of cell life spans and cell fates in various tissues of aged mammals, specifically in humans or in model organisms (e.g., rodents, dogs or nonhuman primates). Letters of intent due Sept. 7; applications due Oct. 7.
New Strategies for Growing 3D Tissues (R01)
NHLBI and NIBIB National Institutes of Health seek to improve our understanding of how cells respond to their environment and to develop accurate assays and methods to understand how organogenesis may instruct the creation of functional 3D engineered cellular aggregates. Letters of intent due Aug. 2; applications due Sept. 1. Also see related R21.
Posted June 3, 2010
Core Centers for Musculoskeletal Biology and Medicine (P30)
NIAMS invites applications for Research Core Centers to provide shared facilities and services to groups of established, currently funded investigators addressing scientific problems in musculoskeletal biology and medicine, in order to improve efficiency, accelerate the pace of research, and ensure greater productivity.
Letters of intent due Sept. 1; applications due Oct. 1.
NCRR Science Education Partnership Award (SEPA) (R25)
NCRR encourages applications for the development and evaluation of innovative research education programs to improve PreK-12 research career opportunities and the community's understanding of the health science advances supported by NIH. Letters of intent due June 28, 2010; May 22, 2011; May 22, 2012/ Applications due July 28, 2010; June 22, 2011; June 22, 2012.
Posted May 24, 2010
Notice of Intent to Publish a Request for Applications for Epigenomic Modifications in Neurodevelopment (R01)
Notice of Intent to Publish a Request for Applications for Epigenomic Modifications in Neurodevelopment (R21)
Notice of Intent to Publish a Request for Applications for Unbiased In Vitro Analysis of Neurobiological Function (R01)
The Central Processing of Taste Information (R01)
NIDCD seeks applications from institutions/organizations studying the role of the central nervous system in the processing of taste information and the perception of taste quality. Opening date: Sept. 5, 2010.
NIGMS National Centers for Systems Biology (P50)
NIGMS seeks grant applications from institutions/ organizations proposing to establish Centers of Excellence in Systems Biology. Letters of intent due Sept.28; applications due Oct. 27, 2010.
NIH Blueprint for Neuroscience Research Competitive Revisions for Studies Focused on Neuropathic Pain or Neural Plasticity to Promote Collaborative Pain Research (R01)
To facilitate the partnering of pain scientists and non-pain neuroscientists from the field of neural plasticity to capture insights and expertise from disciplines where transitions from health to disease have been extensively examined. An expected outcome of this FOA will be the formation of partnerships between pain researchers and non-pain neuroscientists to develop new collaborations focused on understanding the maladaptive neuroplastic changes that occur during the transition from acute to chronic pain. Applications due Sept. 28, 2010, 2011, 2012
Posted May 11, 2010
Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01)
NIH-NSFseek to stimulate quantitative and physical scientists to work with biomedical scientists to transform technological innovation and basic knowledge in the quantitative sciences into new or improved devices or systems for health care. Letters of intent due April 18, 2010, 2011, 2012; applications due May 18, 2010, 2011, 2012.
New Biomedical Frontiers at the Interface of the Life and Physical Sciences (R01)
NIH-NSFseek to encourage grant applications from institutions/organizations that propose discovery research that may create entirely new areas of biomedical investigation through bridging the physical and life/behavioral sciences. Letters of intent due April 18, 2010, 2011, 2012; applications due May 18, 2010, 2011, 2012.
Instructions for Completion and Peer Review of the Vertebrate Animal Section (VAS) in NIH Grant Applications and Cooperative Agreements
Amended NIH Policy on Submission of Late Grant Application Materials Prior to Initial Peer Review
The Role of Cellular Organelles in Alcohol-Induced Tissue Injury (R01)
T o study biological processes involving the cellular organelles in alcohol-induced tissue injury to: (1) better understand how acute or chronic alcohol consumption affects the structure and function of cellular organelles, and in turn, how these changes contribute to alcohol-induced injury; (2) investigate how variations of proteins in cellular organelles, or their regulation and function, including cellular signaling pathways, contribute to an individual's response to acute or chronic alcohol intake and alcohol-induced tissue injury; (3) develop potential biomarkers for prognosis and diagnosis of tissue injury, or identify new targets for therapeutic interventions. Opening date: May 5. See also related R21.
Stress Pathways in Alcohol Induced Organ Injury and Protection (R01)
NIAAA seek applications that propose studying the role of cellular stress responses, the cytoplasmic classical stress response or heat shock response (HSR) and the endoplasmic reticulum (ER) stress, in alcohol-induced tissue injury and tissue protection. See also related R21.
Development of Animal Models and Related Biological Materials For Research (R21)
NCRR encourages applications from institutions/ organizations that propose to develop, characterize or improve animal models for human disease or to improve diagnosis and control diseases of laboratory animals that may interfere with research. Opening date: May 16.
NIH Expands Provisions of the Streamlined Noncompeting Award Process (eSNAP) and Requires Electronic Submission of SNAPs Beginning August 1, 2010
Program Project on Alcohol-Related Research (P01)
NIAAA Program Project Initiative provides leadership in conducting and fostering interdisciplinary research on a wide variety of topics including, but not limited to: the nature, causes, consequences, diagnosis, treatment, and prevention of alcohol abuse and alcoholism; and in developing new topics, approaches and methodologies to pursue these areas of research. Letters of intent due Nov. 2; applications due Dec. 2.
Posted April 12, 2010
NIAMS Accelerating Research Translation (ART) in Musculoskeletal and Skin Tissue Engineering and Regenerative Medicine Competitive Revision Award (R01)
Offer revision support (formerly referred to as a “competing supplement” to active NIAMS R01, P01 and P50 (parent) grants for conducting large animal pre-clinical studies with the potential to immediately lead to human trials in musculoskeletal and skin TE/RM.
Letters of intent due July 5; applications due August 4.
Cross Organ Mechanism-Associated Phenotypes for Genetic Analyses of Heart, Lung, Blood, and Sleep Diseases (MAPGen for HLBS) Research Centers (U01)
This consortium seeks to utilize evolving knowledge of cellular and molecular networks to define common mechanism-associated traits across organ systems. The ultimate goal is to re-define disease at the level of pathogenetic mechanisms and phenotype individuals based on pathobiology, rather than clinical presentation. Letters of intent due August 2; applications due September 1.
Grants for Research in Glomerular Diseases (R01)
To pursue exploratory investigations of glomerular disease, which would foster development of new ideas enhancing the understanding of disease detection, pathogenesis, pre-emption and/ or treatment. Opening date May 5.
Posted March 22, 2010
Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01)
NIH & NSF effort to stimulate quantitative and physical scientists to work with biomedical scientists to transform technological innovation and basic knowledge in the quantitative sciences into new or improved devices or systems for health care. Opens April 18; letters of intent due April 18, 2010, 2011, 2012; applications due May 18, 2010, 2011, 2012.
New Biomedical Frontiers at the Interface of the Life and Physical Sciences (R01)
NIH & NSF effort to encourage grant applications from institutions/organizations that propose discovery research that may create entirely new areas of biomedical investigation through bridging the physical and life/behavioral sciences. Opens April 18; letters of intent due April 18, 2010, 2011, 2012; applications due May 18, 2010, 2011, 2012.
Instructions for Completion and Peer Review of the Vertebrate Animal Section (VAS) in NIH Grant Applications and Cooperative Agreements
Clarifies the information that must be included in the Vertebrate Animal Section (VAS) of grant applications and cooperative agreements (subsequently referred to as applications) that use live vertebrate animals in research, explains how the VAS is evaluated as part of the NIH peer review process.
Amended NIH Policy on Submission of Late Grant Application Materials Prior to Initial Peer Review
Details on new shorter page limits and clarification of the requirement that additional materials must provide evidence of the concurrence of the Authorized Organizational Representative (AOR) is provided.
The Role of Cellular Organelles in Alcohol-Induced Tissue Injury (R01)
NIAAA seeks to: (1) better understand how acute or chronic alcohol consumption affects the structure and function of cellular organelles, and in turn, how these changes contribute to alcohol-induced injury; (2) investigate how variations of proteins in cellular organelles, or their regulation and function, including cellular signaling pathways, contribute to an individual’s response to acute or chronic alcohol intake and alcohol-induced tissue injury; (3) develop potential biomarkers for prognosis and diagnosis of tissue injury, or identify new targets for therapeutic interventions. Opens May 5. (Also see related R21.)
Stress Pathways in Alcohol Induced Organ Injury and Protection (R01)
NIAAA seeks to: (1) acquire insight into how acute or chronic alcohol consumption affects cellular stress pathways and in turn, how these changes contribute to alcohol-induced injury/protection; (2) investigate how alcohol induced stress responses mediate cell survival and death signaling pathways at macromolecular, organelle, cellular and organism level contributing to alcohol-induced tissue injury/protection; (3) develop potential stress related biomarkers for prognosis, diagnosis of tissue injury/protection, furthermore identify new targets for their therapeutic interventions. Opens May 5. (Also see related R21.)
Development of Animal Models and Related Biological Materials For Research (R21)
NCRR,encourages institution/ organization proposals to develop, characterize or improve animal models for human disease or to improve diagnosis and control diseases of laboratory animals that may interfere with research. Opens May 16.
Posted March 19, 2010
Epigenetic Factors Associated with Chronic Disorders (R01)
National Institute of Nursing Research invites applications to stimulate research that addresses underlying epigenetic factors in symptom expression and complications resulting from chronic disorders. It is anticipated that the findings from this research will help 1) identify individuals at the highest risk for developing severe symptoms and complications secondary to chronic disorders, 2) maximize symptom management, and 3) reduce, prevent, or reverse the occurrence of complications.
Forensic DNA Research and Development Grants
Department of Justice (DOJ) seeks applications R&D that can enhance the forensic uses of DNA technology in criminal justice settings. This solicitation focuses on development of technologies that result in faster, more robust, more informative, less costly, or less labor-intensive identification, collection, preservation, and/or analysis of biological evidence that has the potential for DNA analysis. Applications are due by 11:45 p.m. EDT on April 2.
Common Pathogenetic Mechanisms Of Lung Cancer And COPD (R01)
NHLBI and NCI seek to identify the fundamental etiopathogenetic commonalities between lung cancer and Chronic Obstructive Pulmonary Disease (COPD) to characterize: (a) the genotypic and phenotypic characteristics that determine individual susceptibility; and (b) the shared biochemical, molecular, and immunological pathways involved in the origin and progression of the two diseases. Letters of intent due May 18; applications due June 18.
Notice of Availability of Administrative Supplements for Roadmap Assay Development for HTS Awards
NINDS will accept requests until the end of August 2010; they will be reviewed on a monthly basis.
NINDS Announces Availability of Funds for Competitive Revision Applications for Grand Challenge on Optimal Cortical Control of DARPA Revolutionizing Upper-Limb Prosthetics (R01 and R37)
Relates to Grand Challenge on achieving optimal electrocorticography (ECoG) based cortical control of the Revolutionizing Upper-limb Prosthetics 2009 developed by the DARPA. Applications due May 12.
Collaborative Research for Molecular and Genomic Studies of Behavior in Animal Models (R01)
NIGMS and NICHD seek to facilitate collaborative research involving behavioral scientists and investigators with expertise in molecular biology and/or genomics addressing questions about the mechanisms of behavior in animal models. Applications from multiple PIs are encouraged. Opening Date: May 5.
Strategic Partnering to Evaluate Cancer Signatures [SPECS II] (U01)
NCI encourages grant applications for support of the clinical application of multi-analyte molecular signatures derived from comprehensive molecular annotation of tumors. Letters of intent due May 15, 2010; May 15, 2011, May 15, 2012; applications due June 15, 2010, June 15, 2011, June 15, 2012.
Posted February 22, 2010
Notice of Intent to Publish Request for Applications for Core Centers in Musculoskeletal Biology and Medicine (P30)
NIAMS will solicit applications in early 2010 for Core Centers in Musculoskeletal Biology and Medicine designed to enhance research projects aimed at improving the diagnosis, treatment, and prevention of diseases and injuries of the musculoskeletal system and its component tissues. Key public health problems addressed by this research include osteoporosis, osteoarthritis, and muscular dystrophy. Expected application deadline is summer of 2010.
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral MD/PhD and Other Dual Doctoral Degree Fellows (Parent F30)
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (Parent F31)
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (Parent F32)
Posted February 1, 2010
Institutional Clinical and Translational Science Award (U54)
The CTSA initiative assists institutions to create an integrated academic home for Clinical and Translational Science that has the resources to train and advance multi- and inter-disciplinary investigators and research teams with access to innovative research tools and information technologies that apply new knowledge and techniques to patient care. Letters of intent due Sept. 14; applications due Oct. 14.
Posted January 22, 2010
Shared Instrumentation Grant Program (S10)
The NCRR Shared Instrument Grant (SIG) program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instrumentation or an integrated system that costs at least $100,000. The maximum award is $600,000. Types of instruments supported include confocal and electron microscopes, biomedical imagers, mass spectrometers, DNA sequencers, biosensors, cell sorters, X-ray diffraction systems, and NMR spectrometers among others. Applications due March 23.
Posted January 13, 2010
NIH Fiscal Policy for Grant Awards FY 2010
Notice of Legislative Mandates in Effect for FY2010
Salary Limitation on Grants, Cooperative Agreements, and Contracts
NIH Support for Conferences and Scientific Meetings (Parent R13/U13)
A registration process is necessary before submission. Applicants are encouraged to start the process at least four (4) weeks prior to the grant submission date.
Proteomics in Auditory Developmental and Disease Processes (R21)
Posted January 4, 2010
Polycystic Kidney Disease (PKD) Research and Translation Core Centers (P30)
NIDDK seeks applications to support both basic and clinical research on PKD. Core Centers should provide shared institutional and national resources to facilitate basic and clinical research on PKD and improve its effectiveness in translating insights from basic biology to clinical practice.
Letters of intent due February 10; applications due March 10.
Posted December 28, 2009
NIDCD Small Grant Program (R03)
To support basic and clinical research of scientists who are beginning to establish an independent research career. It cannot be used for thesis or dissertation research. The research must be focused on one or more of the areas within the biomedical and behavioral scientific mission of the NIDCD:Â hearing, balance/vestibular, smell, taste, voice, speech, or language. The NIDCD R03 grant mechanism supports different types of projects including secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Irrespective of the type of project, the intent of the NIDCD R03 is for the PD/PI to obtain sufficient preliminary data for a subsequent R01.
Applications due: February 24, 2010, June 29, 2010, and October 29, 2010, February 24, 2011, June 29, 2011, and October 31, 2011, February 24, 2012, June 29, 2012, October 31, 2012.
Gut-Liver-Brain Interactions in Alcohol-Induced Pathogenesis (R01)
NIAAA seeks to stimulate innovative research that will determine (1) how alcohol disrupts gut-liver-brain physiological communications, and (2) how these alterations contribute to the development and exacerbation of alcohol-associated diseases. These investigations are expected to provide a more comprehensive understanding of cellular and molecular mechanisms by which alcohol impairs homeostatic functions at both organ and systemic levels and initiates/promotes tissue injury. Letters of Intent due March 20; applications due April 20.
Gut-Liver-Brain Interactions in Alcohol-Induced Pathogenesis (R21)
See details of R01, above.
Mentored Research Scientist Development Award (Parent K01)
To provide support and “protected time” (three, four, or five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Multiple deadlines.
Independent Scientist Award (Parent K02)
To foster the development of outstanding scientists and enable them to expand their potential to make significant contributions to their field of research. The K02 award provides three, four, or five years of salary support and “protected time” for newly independent scientists who can demonstrate the need for a period of intensive research focus as a means of enhancing their research careers. Multiple deadlines.
Academic Career Award (Parent K07)
To increase the pool of individuals with academic and research expertise to become academic researchers and to enhance the educational or research capacity at the grantee sponsoring grantee institution. The Academic Career Award supports K07 Development awards for more junior level candidates and K07 Leadership awards for more senior individuals with acknowledged scientific expertise and leadership skills.
Multiple deadlines.
Mentored Quantitative Research Development Award (Parent K25)
To attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and “protected time” for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.
Multiple deadlines.
NIH Pathway to Independence Award (Parent K99/R00)
To facilitate a timely transition from a mentored postdoctoral research position to a stable independent research position with independent NIH or other independent research support at an earlier stage than is currently the norm. Multiple deadlines.
NIH Small Research Grant Program (Parent R03)
Supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. For projects that can be carried out in a short period of time with limited resources. Multiple deadlines.
Research Project Grant (Parent R01)
An award made to an institution/organization to support a discrete, specified, circumscribed project to be performed by the named investigator(s) in areas representing the specific interests and competencies of the investigator(s). The R01 research plan proposed by the applicant institution/organization must be related to the stated program interests of one or more of the NIH Institutes and Centers (ICs) based on descriptions of their programs. Multiple deadlines.
Posted December 15, 2009
Membrane Protein Production for Structure Determination (R01)
To develop innovative methods for membrane protein production so that the rate of membrane protein structure determination may be enhanced. Methods development for expression, solubilization, stabilization, purification, characterization, crystallization, and isotopic labeling of membrane proteins to enable the determination of their structures by electron microscopic, x-ray diffraction, nuclear magnetic resonance (NMR), mass spectrometry, and other biophysical techniques are emphasized. Letters of intent due January 11; applications due February 11.
Developing Technologies for Improved In Vivo Epigenetic Imaging or Analysis (R01)
To develop revolutionary technologies that will enable in vivo imaging or analysis of epigenetic changes. The epigenetic features of interest include epigenetic marks, modifying enzymes, effector molecules, the activities of these molecules, or other measures of chromatin state.
Letters of intent due January 4; applications due February 3.
Posted December 1, 2009
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32)
To support predoctoral and postdoctoral research training to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the Nation’s biomedical, behavioral and clinical research agenda. The primary objective is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation.
Ruth L. Kirschstein National Research Service Award Short-Term Institutional Research Training Grants (T35)
To develop or enhance research training opportunities for predoctoral and postdoctoral level individuals interested in careers in biomedical, behavioral and clinical research. Many NIH Institutes and Centers (ICs) use this grant mechanism exclusively to support intensive, short-term research training experiences for students in health professional schools during the summer.
Posted November 2, 2009
Roadmap Transformative Research Projects Program (R01)
NIH Roadmap Transformative Research Awards provide up to $25 million total costs per year for a single project. NIH encourages applications for the Transformative Research Projects Program from scientists representing all disciplines relevant to the NIH mission, including the biological, behavioral, clinical, social, physical, chemical, computational, engineering, and mathematical sciences. Interdisciplinary teams as well as individual investigators with bold ideas are encouraged to apply. Letters of intent due Dec. 22; applications due Jan. 22, 2010.
Development and Characterization of Animal Models for Aging Research (R01)
To promote research that develops, characterizes, refines and enhances model systems for aging research, including but not limited to animal models, cell lines, and informatics. In particular, encourages research to characterize aging at the physiological, biochemical, and functional levels in existing & new animal models, develop unique cell lines for aging research, use comparative biology to identify models of highest priority for aging research, or develop informatics that enhance the utilization of animals for aging research. Opening date: Jan. 5, 2010. Also see related R21.
Enabling Technologies in DNA Repair Research (R21)
To support multidisciplinary teams to develop enabling technologies that will facilitate and stimulate translation of basic research in DNA damage and repair to human population or clinical studies. These projects will develop new tools to measure global DNA repair capacity in individuals or responses in individual DNA repair pathways activated in response to DNA damaging agents. Letters of intent due Dec. 10; applications due Jan. 10, 2010.
Posted October 26, 2009
Cellular and Molecular Mechanisms of Arterial Stiffening and Its Relationship to Development of Hypertension (R01)
NHLBI funding for basic physiological, cellular and molecular investigations to elucidate the mechanisms that lead to conduit artery stiffening in the context of hypertension and explore the temporal relationship between arterial stiffening and the development of hypertension in animal models. Letter of intent due Dec. 21; applications due Jan. 21, 2010.
Bioengineering Research Grants (BRG)(R01)
For basic and applied multi-disciplinary research that addresses important biological, bioengineering or medical research problems. Multi-disciplinary research performed in a single laboratory or by a small number of investigators that applies an integrative, systems approach to develop knowledge and/or methods to prevent, detect, diagnose, or treat disease or to understand health and behavior. Standard application deadlines. Also see related R21.
Posted September 21, 2009
Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01)
For exceptionally innovative research on novel hypotheses or difficult problems, solutions to which would have an extremely high impact on biomedical or biobehavioral research that is germane to the mission of one or more of the participating NIH Institutes. This FOA is for new projects, not continuation of projects that have already been initiated. It does not support pilot projects, i.e., projects of limited scope that are designed primarily to generate data that will enable the PI to seek other funding. Applications are due November 24, 2009.
Posted September 14, 2009
NHLBI Anticipates Issuing a New Funding Opportunity Announcement to Solicit Applications for Basic Research in Cellular and Molecular Mechanisms of Arterial Stiffening and the Relationship to the Development of Hypertension
NHLBI will issue a Funding Opportunity Announcement (FOA) this fall to fund up to 10 R01’s beginning in fiscal year 2010 to support studies aimed at elucidating mechanisms underlying large, conduit artery stiffening in the context of hypertension and studies that examine the temporal relationship between large artery stiffening and the development of hypertension in animal models. Responsive applications must demonstrate the capability to measure arterial stiffening using either established models of hypertension or new animal models developed for this FOA.
Posted August 27, 2009
2010 NIH Directors Pioneer Award Program (DP1)
Supporting individual scientists of exceptional creativity who propose pioneering and possibly transforming approaches to addressing major biomedical or behavioral challenges. Awardees must commit the major portion (at least 51%) of their research effort to activities supported by the Pioneer Award. Applications due October 20.
NIGMS National Centers for Systems Biology (P50)
To promote institutional development of pioneering research, research training, and outreach programs focused on systems-level inquiries of biomedical and biobehavioral questions within the NIGMS mission. Letters of intent due September 28, 2009, 2010, 2011; applications due October 27, 2009, 2010, 2011.
Posted August 3, 2009
Genetic and Genomic Analysis of Xenopus (R01)
To exploit and enhance the power of Xenopus as a vertebrate model for biomedical research, applications should propose to develop new tools or genetic or genomic resources of high priority to the Xenopus research community to advance the detection and characterization of genes, pathways, and phenotypes of interest in development, organogenesis, and in cell biological processes such as cell division, signaling and migration; may also use recently developed genetic and genomic tools or resources. Letters of intent due August 31, 2009, 2010 & 2011; applications due September 30, 2009 2010 & 2011. Also see related R21 and R03 announcements.
Posted July 20, 2009
Awards to Support Research on the Biology of Aging in Invertebrates (R01)
To pursue biology of aging research, applications should focus on the identification, development, and characterization of new invertebrate models that have short lifespans. Invertebrate models with tractable genetics and genome sequence available or in progress, negligible or induced senescence, and tissue regeneration in adults are of particular interest to NIA. Examples of invertebrate models of interest include, but are not limited to planaria, hydra, rotifers, and tunicates. In particular, applications that focus on the characterization of these novel models for aging research utilizing molecular, genetic, cellular or physiological tools and approaches to identify genes involved in longevity, senescence and cellular pathways in tissue homeostasis during aging are encouraged. Applications that propose work on invertebrate models such as Caenorhabditis elegans, Drosophila melanogaster or yeast, Saccharomyces cerevisiae, will be considered non-responsive to this FOA. Letters of intent due September 20; applications due October 30.
Posted July 7, 2009
Announcing a Delay in Transition to Electronic Submission of Applications for Institutional Training and Institutional Career Development Programs
The transition to electronic submission of applications for Institutional National Research Service Awards (T32, T34, T35, T36, T90, TU2), other institutional training grants (D43, D71, T14, T15, T37, U2R) and institutional career development programs (K12 and K30) originally scheduled to occur beginning with submissions due on/after September 25, 2009 has been rescheduled to begin with submission on/after January 25, 2010. These applications should continue to be submitted on paper PHS398 application forms until the January 25 transition.
Mentored Career Award for Faculty at Minority Serving Institutions (K01)
Three-to-five-year non-renewable career development award to support faculty at a minority serving institution for special study and supervised research under a mentor who is an accomplished investigator in the research area proposed and has experience in developing independent investigators. Must be committed to developing into independent biomedical investigators in research areas relevant to the mission of the NHLBI (i.e., cardiovascular, pulmonary, hematologic, or sleep disorders research).
Letters of intent due July 25; applications due August 25.
Mentored Career Development Award to Promote Faculty Diversity/Re-Entry in Biomedical Research (K01)
Three-to-five-year award to support faculty members who are underrepresented on faculty at academic institutions in health-related research on a national or institutional basis, such as individuals from underrepresented racial and ethnic groups, individuals with disabilities, individuals from disadvantaged backgrounds or individuals who have experienced an interruption in their research careers. Basic and clinical research interests must be grounded in the advanced methods and experimental approaches needed to solve problems related to cardiovascular, pulmonary, hematologic, and sleep disorders in the general and health disparities populations. Letters of intent due July 25; applications due August 25.
Cutting-Edge Basic Research Awards (CEBRA) (R21)
To foster highly innovative or conceptually creative research related to drug abuse and addiction and how to prevent and treat them, supporting research that is high-risk and potentially high-impact that is underrepresented or not included in NIDA's current portfolio. Applications due August 21 &December 21, 2009, August 20 & December 21, 2010: August 19 & December 21, 2011.
Posted June 22, 2009
NHLBI Systems Biology Collaborations (R01)
For collaborative systems biology research projects by multi-disciplinary teams to advance our understanding of normal physiology and perturbations associated with heart, lung, blood, and sleep (HLBS) diseases and disorders. Multi-disciplinary expertise across experimental and computational domains is required and the multi-PI mechanism is allowed, as integration across these domains is a critical element of the proposed research plan. Letters of intent due August 14 & December 14, 2009, 2010, 2011. Applications due September 14, 2009; January 13 & September 14, 2010, 2011; January 13, 2012.
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (F32)
To provide support to promising Fellowship Applicants with the potential to become productive, independent investigators in scientific health-related research fields relevant to the missions of participating NIH Institutes and Centers.
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (F33)
For experienced scientists who wish to make major changes in the direction of their research careers or who wish to broaden their scientific background by acquiring new research capabilities as independent investigators in research fields relevant to the missions of participating NIH Institutes and Centers.
Posted June 9, 2009
Advances in Polycystic Kidney Disease (R01)
NIDDK invites experienced and new investigators to submit research grant applications to pursue basic and applied investigations to better understand the etiology and pathogenesis of Polycystic Kidney Disease (PKD), in both its autosomal dominant and autosomal recessive forms. The intent is to intensify investigator-initiated research, to attract new investigators to the field and to increase interdisciplinary research. The ultimate aim is to facilitate PKD-related research studies, which will provide the basis for new therapeutic approaches. Opening Date: September 5, 2009
Posted May 12, 2009
Recovery Act Grand Opportunities GO Grant Submission Deadline Moved to May 29, 2009
Draft Stem Cell Funding Guidelines Issued by NIH for Public Comment
NIH is requesting public comment on draft guidelines entitled "National Institutes of Health Guidelines for Human Stem Cell Research."
Renal Function and Chronic Kidney Disease in Aging (R01)
NIA and NIDDK invite applications that propose basic, clinical, and translational research on chronic kidney disease (CKD) and its consequences in aging and in older persons. Applications should focus on the 1) biology and pathophysiology of CKD in animal models; 2) etiology and pathophysiology of CKD in the elderly; 3) epidemiology and risk factors for the development of CKD with advancing age; and/or 4) diagnosis, medical management and clinical outcomes of CKD in this population.
Renal Function and Chronic Kidney Disease in Aging (R21)
Related to R01 above.
In Vivo Cellular and Molecular Imaging Centers (ICMICs) (P50)
NCI invites new or renewal (competing) applications for P50 Research Center Grants to support interdisciplinary scientific teams conducting cutting-edge cancer molecular imaging research. Letters of intent due September 28, 2009, 2010, 2011; applications dues October 28, 2009, 2010, 2011.
NIH Small Research Grant Program (Parent R03)
The National Institutes of Health (NIH) Investigator-Initiated Small Grant (R03) funding opportunity supports small research projects that can be carried out in a short period of time with limited resources, including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.
NIH Exploratory/Developmental Research Grant Program (Parent R21)
To encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
Posted April 6, 2009
Guidelines for NIH Grant Reviewers
The NIH Office of Extramural Research has posted a new Web page with Guidelines for Reviewers, available from the Peer Review Policies & Practices page. These various guidelines, while intended for reviewers, are also informative for applicants.
Recovery Act Notice: NIH ARRA Funding Considerations for Applications with Meritorious Scores that Fall Beyond the Pay-line
In general, existing applications eligible for consideration of 2-year funding under the economic stimulus package are defined as applications submitted for funding with FY 2008 or FY 2009 funds that: (a) received meritorious priority scores from the initial peer review process; (b) received approval from an Advisory Council or Board prior to September 30, 2009; and (c) received priority scores that could not otherwise be paid in FY 2008 or 2009.
This policy includes consideration of applications in response to previously announced funding opportunities (e.g., RFAs, PAs, PARs), including those that will be peer reviewed by mid-summer and scheduled to receive Advisory Council or Board review prior to September 30, 2009. Individual NIH ICs have more detailed information on their own Web sites regarding specific previously announced funding opportunities being considered for ARRA funding. NIH program directors will contact applicant project directors/principal investigators (PD/PIs) about applications under consideration to discuss potential modifications of the Abstract, Specific Aims, Public Health Relevance, and budget.
ARRA Administrative Supplements and Competitive Revisions: Clarifications on Programmatic Limitations and use of Modular Budgets
In March, 2009, the NIH announced the availability of funds under the American Recovery and Reinvestment Act of 2009 (ARRA) for project expansions via competitive revisions (NOT-OD-09-058) and administrative supplements (NOT-OD-09-056), including administrative supplements providing summer research experiences for students and science educators (NOT-OD-09-060).
This Notice clarifies that requests in response to the Notices cited above may be made in excess of programmatic cost limitations or ceilings associated with a program or activity code (e.g., direct costs stipulated for Small Research Grants [R03], Exploratory/ Developmental Grants [R21]).
If a project was previously funded under a program or activity code with budget limitations or ceilings, these limitations or ceilings are not applicable to ARRA competitive revision and/or administrative supplement requests. Note: All budget requests must be commensurate with the scope of the programmatic request and will be subject to a cost analysis prior to award. In addition, budgets submitted in competing revisions will be subject to the peer review.
Concerning modular budgets and competitive revision applications, the modular grant concept applies.
Recovery Act of 2009: NIH Award Terms and Additional Information for Recipients Receiving Recovery Act Grant Funding
The ARRA requires recipients to separately account for, track, monitor, report on, provide for audit of, and closeout of all grant funding provided under the ARRA. NIH is implementing a number of unique business processes to accommodate the separation of ARRA funding from funding provided under the standard NIH appropriation.
Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers Application
Provides funding for U.S academic institutions/organizations to support the hiring of newly-recruited faculty to develop research projects within the context of Biomedical Core Centers – communities of multidisciplinary researchers focusing on areas of biomedical research relevant to NIH, such as centers, departments, programs, and/or trans-departmental collaborations or consortia. Core Center Grants provide funding to hire, provide appropriate start-up packages, and develop pilot research projects for newly independent investigators, with the goal of augmenting and expanding the institution’s community of multidisciplinary researchers focusing on areas of biomedical research relevant to NIH.
Letters of intent due April 29; applications due May 29.
Posted March 24, 2009
Announcing the FY 2009 NIH Directors Bridge Awards
Updates and expands the NIH Director’s Bridge Award (NDBA) initiated in FY 2007. The NDBA provides continued but limited bridge funding for meritorious investigators who just miss the funding cutoff and have minimal support from other sources. The continued funding will permit the PI additional time to strengthen a resubmission application. An NDBA recipient will receive an R56 award for a single year.
Posted March 10, 2009
NIH Challenge Grants in Health and Science Research (RC1)
Based on funding from the American Recovery and Reinvestment Act of 2009, NIH has designated at least $200 million in FYs 2009 & 2010 for a new initiative called the NIH Challenge Grants in Health and Science Research, to fund 200 or more grants, contingent upon the submission of a sufficient number of scientifically meritorious applications. This program will support research on Challenge Topics that address specific scientific and health research challenges in biomedical and behavioral research that will benefit from significant two-year jumpstart funds. The research in these areas should have a high impact in biomedical or behavioral science and/or public health. Opening date is March 27; applications are due by April 27.
Career Enhancement Award for Stem Cell Research (K18)
To encourage investigators to obtain the training and career development they need to appropriately use stem cells in their research. Human embryonic stem cells (hESC) have only recently become available, and most investigators are not prepared to handle, maintain, or properly study hESCs. Likewise, the potential of human adult or cord blood, and even animal, stem cells for understanding, treating, and curing human disease is great. Opening Date: May 12; standard application deadlines.
Posted February 23, 2009
NHLBI Career Transition Award (K22)
To provide highly qualified postdoctoral fellows an opportunity to receive mentored research experience in the NHLBI Division of Intramural Research and then to provide them with bridge funding to facilitate the transition of their research programs as new investigators at extramural institutions. Standard application dates.
Posted January 27, 2009
Mechanism of Alcohol-Induced Organ Damage (R01)
NIAAA seeks applications to study molecular and cellular mechanisms of alcohol-induced organ damage. NIAAA is especially interested in integrative research that elucidates complex mechanisms of injury either common or unique to each organ system, as well as the study of alcohol’s effect on stem cell, embryonic development, and regeneration. Letters of intent due March 2; applications due April 2.
Enhancing Developmental Biology Research at Undergraduate Institutions Academic Research Enhancement Award (R15)
NICHD encourages grant applications to strengthen the developmental biology research environment at educational institutions that provide baccalaureate or advanced degrees, but that have not been major recipients of NIH support. Also to foster the development of novel or underutilized experimental model systems, and to motivate students through exposure and participation in research projects designed to study fundamental processes underlying normal development. Letters of intent due April 13, 2009, 2010, 2011; applications due May 13, 2009, 2010, 2011.
Established Investigator Award in Cancer Prevention & Control (K05)
The NCI Established Investigator Award provides qualified cancer prevention, control, behavioral, and/or population scientists with protected time to devote to research and to mentoring new investigators. Standard application dates.
The NCI Transition Career Development Award (K22)
Continuation of an NCI program to facilitate the transition of investigators, primarily those with clinical doctoral degrees as well as those with doctoral degrees working in the areas of cancer prevention, control, behavioral, or population science research, from the mentored stage of career development in academic cancer research to the independent stage. Standard application dates.
Posted January 12, 2009
Optimization of Small Molecule Probes for the Nervous System (R21)
NIAAA & NIDA seek to facilitate the discovery of new small molecule probes for investigating biological function in the nervous system by providing funding for advanced medicinal chemistry and the biological testing of compounds. Letters of intent due Feb. 3; applications due March 3.
Career Development Award to Promote Diversity in Neuroscience Research (K01)
To provide support and “protected time” (three, four, or five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Multiple submission dates.
The Effects of Alcohol on Glial Cells (R01)
NIAAA seeks applications to study the effects of alcohol on glial cells, glial gene expression, neuroimmune and proinflammatory signaling, glial survival and the consequences of these effects on glial-neuronal communication, neuronal gene expression, activity and survival and on behavioral effects of alcohol. Letters of intent due Feb. 23; applications dues March 26.
The Effects of Alcohol on Glial Cells (R21)
See R01 details above.
Partnering Awards to Support Collaborative Research on the Biology of Aging (R01)
NIA seeks applications from research partners in the U.S. and the (U.K.) to support collaborative research projects focused on understanding the biology of aging. Letters of intent due Feb. 10; applications due March 10.
NIAMS Small Grant Program for New Investigators (R03)
Small grants to stimulate and facilitate the entry of promising new investigators into research on arthritis and musculoskeletal and skin diseases and injuries. Provides support for pilot research that is likely to lead to a subsequent individual research project grant (R01).
Applications due June 23 & October 23, 2009; June 23 & October 22, 2010; June 23 & October 24, 2011.
Probes for Microimaging The Nervous System (SBIR [R43/R44])
Research and development of probes useful in imaging the structure and function of the brain and other parts of the nervous system, with award duration and amounts greater than those routinely allowed under the SBIR programs. Specifically invites applications that propose research and development of probes that generate signals detectable by one or more imaging modalities. Such probes should indicate the structure or function of molecules or subcellular elements of neurons or other cells of the nervous system. Of special interest are applications that propose research and development of novel probes, although significant enhancements of already existing probes are also invited. Grant applications may propose projects that will result in probes solely intended for use in research or probes that might have clinical utility. Starting dates, opening March 5.
Posted December 3, 2008
Mutant Mouse Regional Resource Centers (U42)
The National Center of Research Resources (NCRR) is soliciting new applications from institutions/organizations to further advance the Mutant Mouse Regional Resource Center (MMRRC) program. The MMRRC goal is to identify, acquire, evaluate, characterize, cryopreserve, and distribute mutant mouse strains to qualified biomedical investigators. A regional network of three repositories operate cooperatively, using a mutually agreed upon, defined set of standard operating procedures to serve the needs of the biomedical research community for transgenic, knockout and other genetically-induced mutant mice. Each center is responsible for importing mice from assigned donating investigators, and establishing banks of cryopreserved sperm, embryos, and related materials for distribution to research investigators. Each center also provides services on a fee-for-service basis which include: cryopreservation of mouse embryos and gametes, rederivation of living mice from cryopreserved embryos and sperm, quality control testing for mouse pathogens, and genotyping services. Applications due March 3, 2009.
Posted October 31, 2008
NIH Supports Research Careers by Repaying Student Loan Debt
NIH is now accepting applications for its extramural Loan Repayment Programs (LRPs), and is letting applicants know through it awareness-raising campaign slogan that "You do the research. NIH will repay your student loans." The LRPs repay up to $35,000 of educational loan debt annually for individuals who commit to conducting at least two years of qualified biomedical or behavioral research at a nonprofit institution of their choice. The annual application cycle started Sept. 1 and will continue until Dec. 1, 2008, for the five extramural LRPs: Clinical Research, Pediatric Research, Health Disparities Research, Contraception and Infertility Research, and Clinical Research for Individuals from Disadvantaged Backgrounds. Visit www.lrp.nih.gov for more details and to apply.
The Mouse Gene Development Initiative (R01)
NIAAA seeks applications that propose to 1) map traits associated with addiction by varying environmental factors at different states of development across inbred strains of mice including using, but not limited to, selective breeding strategies, recombinant inbred mice, the collaborative cross, and haplotype associative mapping with inbred strains; or 2) Identify epigenetic and genetic modifiers that under different environmental and developmental conditions produces different phenotypic outcomes in mice carrying a defined genetic variant, (e.g., knockout, CNVs). Letters of intent due December 29; applications due January 27, 2009.
Posted October 20, 2008
NHLBI Cardiac Development Consortium (U01)
NHLBI and the Canadian Institutes of Health Research (CIHR) invite applications to participate in a new NHLBI Cardiac Development Consortium, a cooperative investigative group that will drive an integrated approach to the investigation of cardiovascular development, leading to a comprehensive understanding of the regulatory networks controlling cardiovascular development. Letters of intent due January 6, 2009; applications due February 6, 2009.
Characterizing the Blood Stem Cell Niche (R01)
NHLBI seeks applications related to the blood stem cell niche, an area critical to advancing stem cell biology and its applications to cellular therapeutics including hematopoietic stem cell transplantation. Development of conditional genetic knock-out models to test the role of factors in specific cell lineages and imaging technology to facilitate following stem cell engraftment in the niche in vivo are integral to this initiative. Letters of intent due December 8; applications due January 6, 2009.
Circadian-Coupled Cellular Function in Heart, Lung, and Blood Tissue (R01)
NHLBI seeks applications aimed at Phase I translation (T1) of recent advances in understanding the molecular basis of endogenous, self-sustaining daily cycles (circadian) in cellular function and gene expression to improve our understanding of heart, lung, and blood disease pathogenesis. Letters of intent due December 8; applications due January 6, 2009.
Web Portal for Nonhuman Primate Research Models (U24)
NCRR seeks applications from institutions/ organizations proposing to develop a comprehensive Web portal presenting extensive information on publicly-funded resources that provide nonhuman primates (NHPs) for research. Applications due January 5, 2009.
Short Courses on Mathematical, Statistical, and Computational Tools for Studying Biological Systems (R25)
NIGMS, NCCAM, NIA, & NIMH seek applications for Research Education Grants (R25) from institutions and organizations to conduct workshops and short courses to improve integration of mathematical, statistical, and computational approaches into biological and/or behavioral research. Support will be limited to activities that reach a wide audience of researchers. The program announcement is NOT intended for university course or curriculum development. Standard application dates.
Posted September 9, 2008
Collaborative Studies on Systems Biology of Complex Phenotypes (R01)
The National Institute of General Medical Sciences (NIGMS) invites applications for collaborative research projects that use systems biology approaches to investigate the mechanisms that underlie genetic determination of complex phenotypes. These projects will combine quantitative modeling approaches and experimental validation of predictive models. It is expected that a team of at least two principal investigators (PIs), one with expertise in systems biology and the other with expertise in the genetics of humans or model organisms, will apply for funding under this FOA. Applications from a single investigator or that propose solely data production and accumulation will be considered non-responsive and will not be reviewed. Applications due November 21, 2008.
Posted August 4, 2008
2009 NSF Graduate Research Fellowship
The National Science Foundation invites appllications for the 2009 Graduate Research Fellowship (NSF-GRFP) competition. This program offers up to 3 years of graduate school support worth over $120,000 to each awardee - last year 913 awards were granted. Benefits include a $30,000 annual stipend, a $10,500 annual cost of education allowance, a one time $1,000 travel allowance, and access to TeraGrid supercomputing facilities. U.S. citizens, nationals, and permanent residents at or near the beginning of their graduate study seeking research-based Master’s and/or PhD degrees in NSF-supported science (including social science and psychology) and engineering disciplines are eligible to apply. The application process is expected to open in August 2008 and close early November 2008. Interested applicants should strongly consider preparing their applications as early as possible to help increase their chances of winning.
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32)
Supports predoctoral, postdoctoral, and short-term research training programs at domestic institutions of higher education to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the U.S. biomedical, behavioral and clinical research. Standard application dates.
Fogarty International Research Collaboration – Basic Biomedical (FIRCA-BB) Research Award (R03)
Facilitates collaborative basic biomedical research between scientists supported by NIH and investigators in low- to middle-income countries. All non-AIDS-related biomedical research topics that are supported by the NIH, including basic, clinical, and applied research that does not involve behavioral or social science topics and techniques, are eligible for inclusion under the FIRCA-BB program. Opening date: August 29; applications due: September 29, 2008; January 28, 2009; May 28, 2009; September 29,2009; January 28, 2010; May 28, 2010; and September 28, 2010.
Posted July 8, 2008
Harnessing Inflammation for Reconstruction of Oral and Craniofacial Tissues (R01)
NIDCR seeks applications that will elucidate the molecular mechanisms of resolution of acute and chronic inflammation, and will develop novel multidisciplinary approaches for predictable control and patterning of tissue inflammatory microenvironments. Will require interdisciplinary and multidisciplinary research that integrates advances in disciplines such as cell and developmental biology, stem cell biology, and immunology, with advances in chemistry, pharmacology, and bioengineering. Multiple PI application strongly encouraged. Letters of intent due Sept. 30; a pplications due Oct. 31. Runs parallel with Exploratory/Developmental (R21) grant (see below).
Harnessing Inflammation for Reconstruction of Oral and Craniofacial Tissues (R21)
Runs parallel with R01 grant (see above). Letters of intent due Sept. 30; applications due Oct. 31.
Posted June 24, 2008
NIGMS National Centers for Systems Biology (P50)
NIGMS invites applications for National Centers for Systems Biology to promote institutional development of pioneering research, research training, and outreach programs focused on systems-level inquiries of biomedical questions within the NIGMS mission. Letters of intent due Sept. 24; applications due Oct. 24.
Integrative Systems Biology Approaches to Auditory Hair Cell Regeneration (R01)
NIDCD invites grant applications using comprehensive systems biology approaches intended to restore lost auditory hair cells and their sensory function following damage to the inner ear from a variety of factors including disease, aminoglycosides, noise, and aging. Runs parallel with NIH Exploratory/Developmental (R21) grant (see below).
Integrative Systems Biology Approaches to Auditory Hair Cell Regeneration (R21)
Runs parallel with R01 grant (see above).
Posted 05/30/08
Core Centers for Musculoskeletal Biology and Medicine (P30)
NIAMS invites applications for Research Core Centers to provide shared facilities and services to groups of established, currently funded investigators addressing scientific problems in musculoskeletal biology and medicine, in order to improve efficiency, accelerate the pace of research, and ensure greater productivity. Letters of intent due June 30; applications due July 30.
Mechanisms of Alcohol-Induced Tissue Injury (R01)
NIAAA and NHLBI are supporting research investigating the Mechanisms of Alcohol Induced Tissue Injury in diverse groups and across the life span. ). Standard receipt dates.
Stem Cells and Cancer (R21)
NCI and NIA encourages research in all aspects of tumor stem cell biology, including the molecular and biochemical regulation of embryonic and adult stem cell behavior relevant to tumor formation. Standard receipt dates.
Posted 04/29/08
Tumor Stem Cells in Cancer Biology, Prevention, and Therapy (P01)
To stimulate research on tumor stem cell biology, including the identification and characterization of specific genetic and functional signatures (e.g., biomarkers) of tumor stem cells. The overall goal is the translation of basic research findings into clinical practice in the contexts of both hematological and solid tumor malignancies. Letters of intent due June 10; applications due July 10.
Genetic Screens to Enhance Zebrafish Research (R01)
Investigator-initiated applications to exploit the power of the zebrafish as a vertebrate model for biomedical and behavioral research. Applications proposing to develop new genetic screens of high priority to the zebrafish community that will advance the detection and characterization of genes, pathways, and phenotypes of interest in development and aging, organ formation, neural processes, behavior, sensory processes, physiological processes, and disease processes are welcome. Letters of intent due August 25, 2008, 2009, 2010; applications due September 24, 2008, 2009, 2010.
Enhancing Zebrafish Research with Research Tools and Techniques (R01)
Investigator-initiated applications to exploit the power of the zebrafish as a vertebrate model for biomedical and behavioral research. Applications proposing to develop new research tools or techniques that are of high priority to the zebrafish community and that will advance the detection and characterization of genes, pathways, and phenotypes of interest in development and aging, organ formation, neural processes, behavior, sensory processing, physiological processes, and disease processes are welcome. Letters of intent due August 17, 2008, 2009, 2010; applications due September 17, 2008, 2009, 2010.
Posted 03/11/08
HHMI Early Career Scientist Competition
The Howard Hughes Medical Institute (HHMI) has announced a new program aimed at researchers who have run their own labs for two to six years and are now at a critical point in establishing their own vibrant, independent research programs. Through a national competition that opens on March 10, HHMI plans to select as many as 70 early career scientists from a wide range of scientific disciplines relevant to biological and medical inquiry. These scientists, most of whom will be assistant professors at the time of the award, will receive six-year, non-renewable appointments to HHMI and receive the substantial research support necessary to move their research in creative, new directions. HHMI will invest more than $300 million in this first group of scientists and plans a second competition in 2011. Applications will be accepted between May 1, 2008, and June 10, 2008, at 2 p.m. ET
Molecular Phenotypes for Lung Diseases (R01)
NHLBI award to stimulate research that will define or subcategorize human lung diseases at a molecular level enabling early diagnosis, prognosis, and personalized treatment of these diseases. The measurement of whole-genome gene expression at the RNA level will be the primary approach to systematically collect molecular phenotyping data for common and rare lung diseases. Letters of intent due April 5; applications due May 5.
Small Grants for Lung Tissue Research (R03)
To promote tissue-based research on COPD (chronic obstructive pulmonary disease) and interstitial fibrotic lung conditions, including studies to establish proof-of-concept in humans for novel mechanisms of pathogenesis. Research must use lung biospecimens and data collected by the Lung Tissue Research Consortium (LTRC). Letters of intent due April 8 & Sept. 22; applications due May 9 & Oct. 17.
Functional Links between the Immune System, Brain Function and Behavior (R01)
Multi-Institute support to study neuroimmune molecules and mechanisms involved in regulating normal and pathological functions of the central nervous system (CNS). Standard receipt dates.
Posted 02/26/08
NIDA Seeks Molecular Biologist to Direct Program in Molecular Neurobiology
Health Scientist Administrator, GS-601-13/14; salary range $82,961-$127,442. Application deadline: March 23, 2008.
Posted 02/06/08
NIH Director’s New Innovator Award
To support a small number of new investigators of exceptional creativity who propose bold and highly innovative new research approaches with the potential to produce a major impact on broad, important problems in biomedical and behavioral research. Applications due March 31.
Shared Instrumentation Grant Program (S10)
To purchase or upgrade commercially available instruments that cost at least $100,000; maximum award is $500,000. Types of instruments supported include confocal and electron microscopes, biomedical imagers, mass spectrometers, DNA sequencers, biosensors, cell sorters, X-ray diffraction systems, and NMR spectrometers among others. Applications due: March 24.
Notice Regarding Authentication of Cultured Cell Lines
NIH believes tmisidentification of cell cultures is a serious problem. However, because authentication methods can be quite specific and are continuously evolving, it would be impractical for NIH to require application of particular methods in all grant applications. The peer review process has been designed to carefully examine the experimental approach and assure that the investigators propose appropriate methods and resources for the described study. Grant applications that fail to employ such practices would not be considered of the highest quality and such manuscripts would not fare well in the journal review process.
NIH Reduces Temporary “Error Correction Window” for Electronic Grant Applications from Five Business Days to Two
NIH has reduced the “error correction window” (i.e. , the time allowed after the submission deadline to address NIH system identified errors/warnings) from five (5) business days to two (2) business days for all electronically submitted grant applications with submission deadlines on or after January 8.
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Predoctoral Training Program in Systems Biology of Developmental Biology & Birth Defects (T32)
Letters of intent due April 25, 2008, 2009 and 2010; applications due May 25, 2008, 2009 and 2010.
Innovative Technologies for Molecular Analysis of Cancer (R21)
Exploratory research projects focused on the inception and early stage development of highly innovative cancer-relevant technologies with emphasis on technically innovative molecular analysis tools with the potential to add a new quality to the investigations of the molecular basis of cancer in vitro, in situ, and/or in vivo. Letters of intent due: April 29, August 24; application due: May 29, September 24.
NIH Administrative Revisions for Human Pluripotent Stem Cell (hPSC) Research Using Non-Embryonic Sources
One-year administrative revisions for NIH-funded grantees to encourage research into the derivation and/or characterization of human pluripotent stem cells (hPSCs) from non-embryonic sources. Applications due April 1.
Thyroid in Aging (R01)
To promote basic, translational, and clinical studies leading to increased understanding of the physiology of the aging thyroid and improved diagnosis and management of thyroid disease in older adults.
Nanoscience and Nanotechnology in Biology and Medicine (R01)
Nanotechnology and nanoscience have the capacity to drive a new wave of medical innovation through the engineering of bioactive nanoscale structures, processes, and systems based on the advancement of our understanding of biology at the nanoscale. Nanoscience and nanotechnology refer to research and development on the understanding and control of matter at a length scale of approximately 1 - 100 nanometers, where novel properties and functions occur because of the size.
NCI Transition Career Development Award to Promote Diversity (K22)
Primarily for those with clinical doctoral degrees as well as those with doctoral degrees working in the areas of cancer prevention, control, behavioral, or population science research, from the mentored stage of career development in academic cancer research to the independent stage.
Posted 01/09/08
Short Courses in Integrative and Organ Systems Pharmacology (R25)
Development and delivery of short courses (2-3 weeks intensive training) to introduce students to the knowledge and skills needed for studies of integrative organ system and whole organism biological responses to drugs and other physiological perturbations
Letters of intent due January 26; applications due February 26.
Nanoscience and Nanotechnology in Biology and Medicine (R01)
A major challenge facing medicine is to develop novel and more sophisticated approaches for the diagnosis, treatment and management of an array of diseases and traumatic injuries. Nanotechnology and nanoscience have the capacity to drive a new wave of medical innovation through the engineering of bioactive nanoscale structures, processes, and systems based on the advancement of our understanding of biology at the nanoscale. Nanoscience and nanotechnology refer to research and development on the understanding and control of matter at a length scale of approximately 1 - 100 nanometers, where novel properties and functions occur because of the size.
Nanoscience and Nanotechnology in Biology and Medicine (R21)
See details above.
NCI Transition Career Development Award to Promote Diversity (K22)
To facilitate the transition of investigators from minority groups underrepresented in biomedical research, primarily those with clinical doctoral degrees as well as those with doctoral degrees working in the areas of cancer prevention, control, behavioral, or population science research, from the mentored stage of career development in academic cancer research to the independent stage.
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Predoctoral Training Program in Systems Biology of Developmental Biology & Birth Defects (T32)
National Institute of Child Health and Human Development (NICHD)
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