Urinary System

How does the wall of the collecting duct located in the renal papilla achieve impermeability to water given the fact that lipid bilayers are permeable?

 

The relative permeability of the papillary collecting ducts to water is dependent on the circulating levels of Antidiuretic Hormone (ADH). ADH is produced in the brain's hypothalamus and released from axons in the neurohypophysis (posterior part of the pituitary gland). In the kidney, this hormone acts to open water channels in the cells lining the papillary collecting ducts. The higher the circulating levels of ADH, the more permeable to water the papillary collecting ducts become.

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