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Annual Meeting at Experimental Biology 2017
Applied Anatomy-Human Development and Disease Mini-Meeting
Sunday, April 23
Room 176AB
​Sunday, April 23, 8:30 am – 10:00 am (Room 176AB)
Organoids: Recapitulating Anatomy in a Dish Plenary Session
Applied Anatomy - Human Development and Disease Mini-Meeting
Chair – Kenneth Kramer (Creighton University)
Embryonic and adult mammalian stem cells can remarkably self-organize and differentiate in 3D culture. Because the resulting organoids mirror many of the anatomical and functional properties of the organs, organoids are being used to model human organ development and disease, opening up new possibilities for regenerative medicine. Speakers will discuss their insights gained from studies of several organoids, including intestine, pancreas, inner ear, and lung.
              Hans Clevers (Hubrecht Institute)
              Lgr5 Stem Cell-based Organoids in Human Disease
              Eri Hashino (Indiana University)
              Modeling Inner Ear Development with Pluripotent Stem Cells in 3D Culture
              Jason Spence (University of Michigan)
              Modeling Human Development Using Insights from Organoids and Embryo

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​Sunday, April 23, 10:30 am – 12:00 pm (Room 176AB)
Body on-Chip and 3D Culture
Applied Anatomy - Human Development and Disease Mini-Meeting
Chair – Aloysius Klingelhutz (University of Iowa)
                Aloysius Klingelhutz (University of Iowa)
                Body On-chip and 3D Culture: An Overview
                Megan McCain (University of Southern California)
                Engineering Microphysiological Models of Human Cardiac and Skeletal Muscle Disease
                Dan Dongeun Huh (University of Pennsylvania)
                Microengineered Physiological Biomimicry: Human Organ-on-Chips

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​Sunday, April 23, 2:00 pm – 3:30 pm (Room 176AB)
Induced Pluripotent Stem Cells and their Translational Applications
Applied Anatomy - Human Development and Disease Mini-Meeting
Chair – Rajasingh Johnson (University of Kansas Medical Center)
                Sang Jin Lee (Wake Forest School of Medicine)
                3D Integrated Tissue and Organ Printing System to Produce Human Body Parts with Structural Integrity
                Arghya Paul (University of Kansas)
                Engineering Nanobioactive Hydrogels for Stem cells and Regenerative Medicine
                Rajasingh Johnson (University of Kansas Medical Center)
                Generation of Functional Cardiomyocytes Derived from Human Somatic Cells and Therapy for Heart                         Diseases

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Sunday, April 23, 4:00 pm – 5:30 pm (Room 176AB)
Advances and Novel Approaches Illuminating Brain Development and Disorders
Co-sponsored by Developmental Dynamics
Applied Anatomy - Human Development and Disease Mini-Meeting

Chair – Gary Schoenwolf (University of Utah School of Medicine)
The session will examine the genetic and epigenetic mechanisms regulating the development of neuronal circuits, behavior, and brain disorders.
                Raunak Basu (University of Utah School of Medicine)
                Selective Cell Adhesion Drives Synaptic Specificity in the Hippocampus
                Daniel Kerschensteiner (Washington University School of Medicine)
                Molecular Mechanisms of Retinal Circuit Assembly
                Chris Gregg (University of Utah School of Medicine)
                Novel Allele-Specific Epigenetic Effects Shape Genetic Architecture in the Brain

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