Member Spotlight: Dr. Kaleb Sellers - Unveiling the Intricacies of Vertebrate Anatomy

Anatomy Now - March 6, 2024

Dr. Kaleb Sellers is a dedicated explorer, unraveling the mysteries of comparative vertebrate anatomy and evolution. Currently serving as a Postdoctoral Scholar in the Ross lab at the Univ. of Chicago, Dr. Sellers' expertise spans across various dimensions of the field, including the comparative functional morphology of the feeding system and vertebrate paleontology. His current focus, however, lies in the intricate anatomy of the tongue, with an emphasis on primates, including our hominoid ancestors.

Research Prowess: From Crocodilians to Primates

Dr. Sellers' journey in academia has been marked by a relentless pursuit of knowledge, evident in his dissertation research looking into the functional effects of skull flattening on the jaw muscles and joints within the lineage leading to crocodilians. This research not only added valuable insights to the understanding of crocodilian evolution but showcased Dr. Sellers' adeptness in exploring the nuances of anatomy across diverse species.

His current postdoctoral endeavors take center stage in characterizing the basic and functional anatomy of the hyolingual apparatus across mammals, with a keen focus on primates. Employing cutting-edge techniques such as contrast-enhanced CT scanning, morphometrics, and engineering methods, Dr. Sellers dissects the complexities of muscle anatomy and assesses muscle forces. This multidisciplinary approach adds layers of precision to his work, offering a comprehensive understanding of the structures that drive feeding systems in mammals.

Tongue Tales: The Primate Hyolingual Apparatus

 Swallowing is something we do hundreds of times every day.  It’s easy to take for granted that there is an understanding of how the process works, which is not necessarily the case. “When Callum [Ross] told me we don’t know how we swallow, I said what do you mean? You don’t notice it until it doesn’t work and then you notice it very keenly.”

Dr. Sellers is exploring the anatomy and function of the tongue in primates and their close relatives. The utilization of XROMM (X-ray Reconstruction of Moving Morphology) and DC T methods allows him to scrutinize the complex musculature and hydrostatic nature of tongue movement during swallowing,”The roles of som of the soft tissues aren’t very clear…instead of placing markers just in the bony elements, we’re also placing them within the tongue to see which parts of the tongue move in which ways during phases of swallowing”. This not only contributes to our fundamental understanding of primate anatomy but also sheds light on the evolutionary adaptations that have shaped the feeding mechanisms in these creatures.

The implications of Dr. Sellers' work extend beyond the boundaries of academia. By delving into the clinical aspects of his research, he seeks to unravel potential connections to conditions such as dysphagia or oropharyngeal cancers. This bridges the gap between basic science and practical applications, showcasing
the real-world significance of his contributions to anatomical research.

His commitment to unraveling the intricacies of anatomy has earned him the AAA Early Career Anatomist Publication Award, recognizing his outstanding contributions to the field. 

Mentoring and Guiding the Next Generation

 Dr. Sellers' impact goes beyond the laboratory. As a mentor, he plays a pivotal role in shaping the future of anatomical research. Actively involved in guiding junior graduate students, he encourages them to find their research niche and navigate the complex terrain of academia. His mentorship extends beyond the technicalities of research, fostering an environment where young minds can thrive and contribute meaningfully to the scientific community.

Understanding the challenges faced by aspiring researchers, Dr. Sellers is dedicated to imparting the importance of research and anatomy in their chosen fields. By instilling a sense of purpose and curiosity, he empowers students to recognize the profound impact of their work, fostering a new generation of researchers poised to make significant contributions to the field.

Charting the Course Ahead

Dr. Kaleb Sellers' multifaceted approach to the study of comparative vertebrate anatomy, coupled with a dedication to mentorship, paints a vivid picture of a scientist shaping the future of the field. As Dr. Sellers continues to unravel the mysteries of the hyolingual apparatus in primates and contributes to the broader understanding of vertebrate anatomy, his work serves as an inspiration for fellow researchers and a beacon for aspiring anatomists. In the intricate tapestry of scientific inquiry, Dr. Sellers has woven a thread that connects the past, present, and future of anatomical exploration, leaving an indelible mark on the landscape of evolutionary biology and comparative anatomy.